Crimean-Congo Hemorrhagic Fever Virus suppresses Innate Immune Responses via a Ubiquitin and ISG15 Specific Protease

Antiviral responses are regulated by conjugation of ubiquitin (Ub) and interferon-stimulated gene 15 (ISG15) to proteins. Certain classes of viruses encode Ub- or ISG15-specific proteases belonging to the ovarian tumor (OTU) superfamily. Their activity is thought to suppress cellular immune response...

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Publicat a:Cell Rep
Autors principals: Scholte, Florine E.M., Zivcec, Marko, Dzimianski, John V., Deaton, Michelle K., Spengler, Jessica R., Welch, Stephen R., Nichol, Stuart T., Pegan, Scott D., Spiropoulou, Christina F., Bergeron, Éric
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616139/
https://ncbi.nlm.nih.gov/pubmed/28877473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.040
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