The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages

BACKGROUND: The interaction of asbestos with macrophages drives two key processes that are linked to malignancy: (1) the generation of reactive oxygen species (ROS)/reactive nitrogen species (RNS) and (2) the activation of an inflammation cascade that drives acute and chronic inflammation, with the...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Pietrofesa, Ralph A., Woodruff, Patrick, Hwang, Wei-Ting, Patel, Priyal, Chatterjee, Shampa, Albelda, Steven M., Christofidou-Solomidou, Melpo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615985/
https://ncbi.nlm.nih.gov/pubmed/29075366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7395238
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