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Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)

The interaction of asbestos fibers with macrophages generates harmful reactive oxygen species (ROS) and subsequent oxidative cell damage that are key processes linked to malignancy. Secoisolariciresinol diglucoside (SDG) is a non-toxic, flaxseed-derived pluripotent compound that has antioxidant prop...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pietrofesa, Ralph A., Velalopoulou, Anastasia, Albelda, Steven M., Christofidou-Solomidou, Melpo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813184/
https://ncbi.nlm.nih.gov/pubmed/26938529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030322
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