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Bacterial D-Amino Acids Suppress Sinonasal Innate Immunity Through Sweet Taste Receptors in Solitary Chemosensory Cells

In the upper respiratory epithelium, bitter and sweet taste receptors present in solitary chemosensory cells influence antimicrobial innate immune defense responses. Whereas activation of the bitter taste receptor (T2R) stimulates surrounding epithelial cells to release antimicrobial peptides, activ...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Lee, Robert J., Hariri, Benjamin M., McMahon, Derek B., Chen, Bei, Doghramjii, Laurel, Adappa, Nithin D., Palmer, James N., Kennedy, David W., Jiang, Peihua, Margolskee, Robert F., Cohen, Noam A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615852/
https://ncbi.nlm.nih.gov/pubmed/28874606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aam7703
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