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Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein

BACKGROUND: Ischemia/reperfusion injury (I/R) is an important pathophysiology of post-cardiac arrest syndrome (PCAS) against multiple organ dysfunction and mortality. The inflammatory response in PCAS causes systemic I/R. The purpose of this study was to demonstrate the pathophysiology of systemic I...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Sugita, Atsunori, Kinoshita, Kosaku, Sakurai, Atsushi, Chiba, Nobutaka, Yamaguchi, Junko, Kuwana, Tsukasa, Sawada, Nami, Hori, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615459/
https://ncbi.nlm.nih.gov/pubmed/28950909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-017-1828-5
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