Osteopontin deficiency aggravates hepatic injury induced by ischemia–reperfusion in mice

Osteopontin (OPN) is a multifunctional protein involved in hepatic steatosis, inflammation, fibrosis and cancer progression. However, its role in hepatic injury induced by ischemia–reperfusion (I–R) has not yet been investigated. We show here that hepatic warm ischemia for 45 min followed by reperfu...

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Autors principals: Patouraux, S, Rousseau, D, Rubio, A, Bonnafous, S, Lavallard, V J, Lauron, J, Saint-Paul, M-C, Bailly-Maitre, B, Tran, A, Crenesse, D, Gual, P
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047890/
https://ncbi.nlm.nih.gov/pubmed/24810044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.174
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