Osteopontin deficiency aggravates hepatic injury induced by ischemia–reperfusion in mice

Osteopontin (OPN) is a multifunctional protein involved in hepatic steatosis, inflammation, fibrosis and cancer progression. However, its role in hepatic injury induced by ischemia–reperfusion (I–R) has not yet been investigated. We show here that hepatic warm ischemia for 45 min followed by reperfu...

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Autori principali: Patouraux, S, Rousseau, D, Rubio, A, Bonnafous, S, Lavallard, V J, Lauron, J, Saint-Paul, M-C, Bailly-Maitre, B, Tran, A, Crenesse, D, Gual, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047890/
https://ncbi.nlm.nih.gov/pubmed/24810044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.174
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