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Biochemical Regulatory Features of Activation-Induced Cytidine Deaminase Remain Conserved from Lampreys to Humans

Activation-induced cytidine deaminase (AID) is a genome-mutating enzyme that initiates class switch recombination and somatic hypermutation of antibodies in jawed vertebrates. We previously described the biochemical properties of human AID and found that it is an unusual enzyme in that it exhibits b...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Quinlan, Emma M., King, Justin J., Amemiya, Chris T., Hsu, Ellen, Larijani, Mani
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615186/
https://ncbi.nlm.nih.gov/pubmed/28716949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00077-17
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