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TAU(45-230) ASSOCIATION WITH THE CYTOSKELETON AND MEMBRANE-BOUND ORGANELLES: FUNCTIONAL IMPLICATIONS IN NEURODEGENERATION
The dysregulation of posttranslational modifications of the microtubule-associated protein (MAP) tau plays a key role in Alzheimer’s disease (AD) and related disorders. Thus, we have previously shown that beta amyloid (Aβ)-induced neurotoxicity was mediated, at least in part, by tau cleavage into th...
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| Veröffentlicht in: | Neuroscience |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5614872/ https://ncbi.nlm.nih.gov/pubmed/28844006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.08.026 |
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