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Quantitative analysis of hemin-induced neutrophil extracellular trap formation and effects of hydrogen peroxide on this phenomenon

Formation of neutrophil extracellular traps (NETs) can perpetuate sterile inflammation; thus, it is important to clarify their pathophysiological characteristics. Free heme, derived via hemolysis, is a major contributor to organ damage, and reportedly induces neutrophil activation as well as reactiv...

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Publicado en:Biochem Biophys Rep
Main Authors: Ohbuchi, Ayako, Kono, Mari, Kitagawa, Kaihei, Takenokuchi, Mariko, Imoto, Shion, Saigo, Katsuyasu
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614717/
https://ncbi.nlm.nih.gov/pubmed/28955779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.07.009
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