Deferasirox, an iron-chelating agent, alleviates acute lung inflammation by inhibiting neutrophil activation and extracellular trap formation

OBJECTIVE: Reactive oxygen species (ROS) production by neutrophils induces pulmonary endothelial cell damage and results in acute lung injury (ALI). We previously reported that deferasirox (DFS), an iron-chelating agent, inhibits the ROS production and neutrophil extracellular trap (NET) formation i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Int Med Res
Main Authors: Kono, Mari, Matsuhiroya, Shiori, Obuchi, Ayako, Takahashi, Takayuki, Imoto, Shion, Kawano, Seiji, Saigo, Katsuyasu
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2020
Teme:
Pre-Clinical Research Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503029/
https://ncbi.nlm.nih.gov/pubmed/32938287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060520951015
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki