Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technology

ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myost...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Sakamoto, Kotaro, Kanematsu-Yamaki, Yoko, Kamada, Yusuke, Oka, Masahiro, Ohnishi, Toshiyuki, Miwa, Masanori, Asami, Taiji, Inooka, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614685/
https://ncbi.nlm.nih.gov/pubmed/28955765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.06.001
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