Bioengineered Bruch's-like extracellular matrix promotes retinal pigment epithelial differentiation

In the eye, the retinal pigment epithelium (RPE) adheres to a complex protein matrix known as Bruch's membrane (BrM). The aim of this study was to provide enriched conditions for RPE cell culture through the production of a BrM-like matrix. Our hypothesis was that a human RPE cell line would de...

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Bibliographic Details
Published in:Biochem Biophys Rep
Main Authors: McLenachan, Samuel, Hao, Erwei, Zhang, Dan, Zhang, Ling, Edel, Michael, Chen, Fred
Format: Artigo
Language:Inglês
Published: Elsevier 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614661/
https://ncbi.nlm.nih.gov/pubmed/28955745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.03.008
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