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The EGLN-HIF O(2) Sensing System: Multiple Inputs and Feedbacks
The EGLN (also called PHD) prolyl hydroxylase enzymes and their canonical targets, the HIFα subunits, represent the core of an ancient oxygen-monitoring machinery used by metazoans. In this review we highlight recent progress in understanding the overlapping versus specific roles of EGLN enzymes and...
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| Publicado en: | Mol Cell |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5613951/ https://ncbi.nlm.nih.gov/pubmed/28622522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.06.002 |
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