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Hypoxia-Activated Alkylating Agents in BRCA1-Mutant Ovarian Serous Carcinoma
Breast cancer 1 antigen (BRCA 1) and breast cancer 2 antigen (BRCA2) genes play a significant role in deoxyribonucleic acid (DNA) repair by means of interstrand crosslink repair, and deleterious germline mutations of these are responsible for most hereditary breast and ovarian cancers. Therapeutic s...
Bewaard in:
| Gepubliceerd in: | Cureus |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cureus
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5613928/ https://ncbi.nlm.nih.gov/pubmed/28959512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.1517 |
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