Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function

On acquisition of an oncogenic mutation, primary human and mouse cells can enter oncogene-induced senescence (OIS). OIS is characterized by a stable proliferation arrest and secretion of proinflammatory cytokines and chemokines, the senescence-associated secretory phenotype. Proliferation arrest and...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: van Tuyn, John, Jaber-Hijazi, Farah, MacKenzie, Douglas, Cole, John J., Mann, Elizabeth, Pawlikowski, Jeff S., Rai, Taranjit Singh, Nelson, David M., McBryan, Tony, Ivanov, Andre, Blyth, Karen, Wu, Hong, Milling, Simon, Adams, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613751/
https://ncbi.nlm.nih.gov/pubmed/28647344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.05.030
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