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A microRNA cluster (let-7c, miRNA-99a, miRNA-125b, miRNA-155 and miRNA-802) encoded at chr21q21.1-chr21q21.3 and the phenotypic diversity of Down’s syndrome (DS; trisomy 21)

Down’s syndrome (DS) is the most common genetic cause of intellectual disability and cognitive deficit attributable to a naturally-occurring abnormality of gene dosage. DS is caused by a triplication of all or part of human chromosome 21 (chr21) and currently there are no effective treatments for th...

詳細記述

保存先:
書誌詳細
出版年:J Nat Sci
主要な著者: Zhao, Yuhai, Jaber, Vivian, Percy, Maire E., Lukiw, Walter J.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613287/
https://ncbi.nlm.nih.gov/pubmed/28959732
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