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The EspF N-Terminal of Enterohemorrhagic Escherichia coli O157:H7 EDL933w Imparts Stronger Toxicity Effects on HT-29 Cells than the C-Terminal

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 EspF is an important multifunctional protein that destroys the tight junctions of intestinal epithelial cells and promotes host cell apoptosis. However, its molecular mechanism remains elusive. We knocked out the espF sequence (747 bp, ΔespF), N-term...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Wang, Xiangyu, Du, Yanli, Hua, Ying, Fu, Muqing, Niu, Cong, Zhang, Bao, Zhao, Wei, Zhang, Qiwei, Wan, Chengsong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613159/
https://ncbi.nlm.nih.gov/pubmed/28983470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00410
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