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Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important foodborne pathogen that can cause bloody diarrhea and hemolytic uremic syndrome (HUS) in humans. EspF is one of the best-characterized effector proteins secreted from the type three secretion system to hijack host cell functions. Howe...

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Publicat a:Front Cell Dev Biol
Autors principals: Hua, Ying, Wu, Jiali, Fu, Muqing, Liu, Jinyue, Li, Xiaoxia, Zhang, Bao, Zhao, Wei, Wan, Chengsong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785878/
https://ncbi.nlm.nih.gov/pubmed/33425920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.613061
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