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Resolving distinct molecular origins for copper effects on PAI-1

Components of the fibrinolytic system are subjected to stringent control to maintain proper hemostasis. Central to this regulation is the serpin plasminogen activator inhibitor-1 (PAI-1), which is responsible for specific and rapid inhibition of fibrinolytic proteases. Active PAI-1 is inherently uns...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: Bucci, Joel C., McClintock, Carlee S., Chu, Yuzhuo, Ware, Gregory L., McConnell, Kayla D., Emerson, Joseph P., Peterson, Cynthia B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613068/
https://ncbi.nlm.nih.gov/pubmed/28913669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-017-1489-5
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