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Predicting metabolic adaptation from networks of mutational paths
Competition for substrates is a ubiquitous selection pressure faced by microbes, yet intracellular trade-offs can prevent cells from metabolizing every type of available substrate. Adaptive evolution is constrained by these trade-offs, but their consequences for the repeatability and predictability...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5612958/ https://ncbi.nlm.nih.gov/pubmed/28947804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00828-6 |
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