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Predicting metabolic adaptation from networks of mutational paths

Competition for substrates is a ubiquitous selection pressure faced by microbes, yet intracellular trade-offs can prevent cells from metabolizing every type of available substrate. Adaptive evolution is constrained by these trade-offs, but their consequences for the repeatability and predictability...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Josephides, Christos, Swain, Peter S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612958/
https://ncbi.nlm.nih.gov/pubmed/28947804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00828-6
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