Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I

A key feature of meiosis is the step-wise removal of cohesin, the protein complex holding sister chromatids together, first from arms in meiosis I and then from the centromere region in meiosis II. Centromeric cohesin is protected by Sgo2 from Separase-mediated cleavage, in order to maintain sister...

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Publicado no:Nat Commun
Main Authors: El Yakoubi, Warif, Buffin, Eulalie, Cladière, Damien, Gryaznova, Yulia, Berenguer, Inés, Touati, Sandra A., Gómez, Rocío, Suja, José A., van Deursen, Jan M., Wassmann, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612927/
https://ncbi.nlm.nih.gov/pubmed/28947820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00774-3
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