Statins decrease vascular epithelial growth factor expression via down-regulation of receptor for advanced glycation end-products

AIMS: Statins, inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, possess pleiotropic effects that have been extended to modulation of various cellular behaviors. This study aimed to examine whether statins modulate vascular endothelial growth factor A (VEGF-A) expression in human retina...

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Bibliografiske detaljer
Udgivet i:Heliyon
Main Authors: Tsujinaka, Hiroki, Itaya-Hironaka, Asako, Yamauchi, Akiyo, Sakuramoto-Tsuchida, Sumiyo, Shobatake, Ryogo, Makino, Mai, Masuda, Naonori, Hirai, Hiromasa, Takasawa, Shin, Ogata, Nahoko
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612812/
https://ncbi.nlm.nih.gov/pubmed/28971147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00401
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