Combinatorial signal perception in the BMP pathway

The Bone Morphogenetic Protein (BMP) signaling pathway comprises multiple ligands and receptors that interact promiscuously with one another, and typically appear in combinations. This feature is often explained in terms of redundancy and regulatory flexibility, but it has remained unclear what sign...

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Veröffentlicht in:Cell
Hauptverfasser: Antebi, Yaron E., Linton, James M., Klumpe, Heidi, Bintu, Bogdan, Gong, Mengsha, Su, Christina, McCardell, Reed, Elowitz, Michael B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612783/
https://ncbi.nlm.nih.gov/pubmed/28886385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.015
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