Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport

Various bacterial toxins circumvent host defenses through overproduction of cAMP. In a previous study, we showed that edema factor (EF), an adenylate cyclase from Bacillus anthracis, disrupts endocytic recycling mediated by the small GTPase Rab11. As a result, cargo proteins such as cadherins fail t...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Guichard, Annabel, Jain, Prashant, Moayeri, Mahtab, Schwartz, Ruth, Chin, Stephen, Zhu, Lin, Cruz-Moreno, Beatriz, Liu, Janet Z., Aguilar, Bernice, Hollands, Andrew, Leppla, Stephen H., Nizet, Victor, Bier, Ethan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612732/
https://ncbi.nlm.nih.gov/pubmed/28945820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006603
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