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Nuclear insulin-like growth factor-1 receptor (IGF1R) displays proliferative and regulatory activities in non-malignant cells

The insulin-like growth factor-1 receptor (IGF1R) mediates the biological actions of IGF1 and IGF2. The IGF1R is involved in both physiological and pathological activities and is usually overexpressed in most types of cancer. In addition to its classical mechanism of action, recent evidence has show...

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Pubblicato in:PLoS One
Autori principali: Solomon-Zemler, Ravid, Sarfstein, Rive, Werner, Haim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612648/
https://ncbi.nlm.nih.gov/pubmed/28945762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185164
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