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Differential Effects of Insulin and IGF1 Receptors on ERK and AKT Subcellular Distribution in Breast Cancer Cells

Insulin and insulin-like growth factor-1 (IGF1) have important roles in breast cancer development. The recent identification of nuclear insulin (INSR) and IGF1 (IGF1R) receptors provides a novel paradigm in the area of signal transduction. The fact that INSR and IGF1R can function as transcription f...

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Publicado en:Cells
Autores principales: Sarfstein, Rive, Nagaraj, Karthik, LeRoith, Derek, Werner, Haim
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952817/
https://ncbi.nlm.nih.gov/pubmed/31771180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121499
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