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A Human Glioblastoma Organotypic Slice Culture Model for Study of Tumor Cell Migration and Patient-specific Effects of Anti-Invasive Drugs

Glioblastoma (GBM) continues to carry an extremely poor clinical prognosis despite surgical, chemotherapeutic, and radiation therapy. Progressive tumor invasion into surrounding brain parenchyma represents an enduring therapeutic challenge. To develop anti-migration therapies for GBM, model systems...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Parker, Jonathon J., Lizarraga, Marcela, Waziri, Allen, Foshay, Kara M.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612552/
https://ncbi.nlm.nih.gov/pubmed/28784966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53557
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