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A Human Glioblastoma Organotypic Slice Culture Model for Study of Tumor Cell Migration and Patient-specific Effects of Anti-Invasive Drugs

Glioblastoma (GBM) continues to carry an extremely poor clinical prognosis despite surgical, chemotherapeutic, and radiation therapy. Progressive tumor invasion into surrounding brain parenchyma represents an enduring therapeutic challenge. To develop anti-migration therapies for GBM, model systems...

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Foilsithe in:J Vis Exp
Main Authors: Parker, Jonathon J., Lizarraga, Marcela, Waziri, Allen, Foshay, Kara M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MyJove Corporation 2017
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612552/
https://ncbi.nlm.nih.gov/pubmed/28784966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53557
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