Proteasome impairment by α-synuclein

Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder worldwide and characterized by the loss of dopaminergic neurons in the patients’ midbrains. Both the presence of the protein α-synuclein in intracellular protein aggregates in surviving neurons and the genetic linking o...

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Pubblicato in:PLoS One
Autori principali: Zondler, Lisa, Kostka, Marcus, Garidel, Patrick, Heinzelmann, Udo, Hengerer, Bastian, Mayer, Benjamin, Weishaupt, Jochen H., Gillardon, Frank, Danzer, Karin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612461/
https://ncbi.nlm.nih.gov/pubmed/28945746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184040
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