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Cells lay their own tracks – optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration

Rho GTPase family members are known regulators of directed migration and therefore play key roles in processes including development, the immune response and cancer metastasis. However, their individual contributions to these processes are complex. Here, we modify the activity of the two Rho GTPase...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Sci
Hauptverfasser: Zimmerman, Seth P., Asokan, Sreeja B., Kuhlman, Brian, Bear, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612177/
https://ncbi.nlm.nih.gov/pubmed/28754687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.205948
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