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Checks and balances for the iron bank
The RNA-binding iron regulatory proteins IRP1 and IRP2 are inactivated by either Fe-S cluster insertion or protein degradation mediated by the E3 ligase component FBXL5. However, the mechanisms for coordination between Fe-S cluster assembly, FBXL5, and IRP1/IRP2 activity are poorly defined. A new st...
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| Publicado no: | J Biol Chem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5612128/ https://ncbi.nlm.nih.gov/pubmed/28939752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H117.785741 |
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