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The UL8 subunit of the helicase–primase complex of herpes simplex virus promotes DNA annealing and has a high affinity for replication forks

During lytic infection, herpes simplex virus (HSV) DNA is replicated by a mechanism involving DNA recombination. For instance, replication of the HSV-1 genome produces X- and Y-branched structures, reminiscent of recombination intermediates. HSV-1's replication machinery includes a trimeric hel...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bermek, Oya, Weller, Sandra K., Griffith, Jack D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612096/
https://ncbi.nlm.nih.gov/pubmed/28743747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.799064
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