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Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE

Dystonia is the third most common movement disorder, but its diagnosis and treatment remain challenging. One of the most severe types of dystonia is early-onset torsion dystonia (EOTD). The best studied and validated EOTD-associated mutation, torsinAΔE, is a deletion of a C-terminal glutamate residu...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Zacchi, Lucía F., Dittmar, John C., Mihalevic, Michael J., Shewan, Annette M., Schulz, Benjamin L., Brodsky, Jeffrey L., Bernstein, Kara A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611967/
https://ncbi.nlm.nih.gov/pubmed/28768697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.029926
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