Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve

Correct myelination is crucial for the function of the peripheral nervous system. Both positive and negative regulators within the axon and Schwann cell function to ensure the correct onset and progression of myelination during both development and following peripheral nerve injury and repair. The S...

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Publicado no:Development
Main Authors: Roberts, Sheridan L., Dun, Xin-peng, Doddrell, Robin D. S., Mindos, Thomas, Drake, Louisa K., Onaitis, Mark W., Florio, Francesca, Quattrini, Angelo, Lloyd, Alison C., D'Antonio, Maurizio, Parkinson, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611958/
https://ncbi.nlm.nih.gov/pubmed/28743796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.150656
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