Nanobody based Immunoassay for Human Soluble Epoxide Hydrolase Detection using PolyHRP for Signal Enhancement—the Rediscovery of PolyHRP?

Soluble epoxide hydrolase (sEH) is a potential pharmacological target for treating hypertension, vascular inflammation, cancer, pain and multiple cardiovascular related diseases. A variable domain of the heavy chain antibody (termed sdAb, nanobody or VHH) possesses advantages of small size, high sta...

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Gepubliceerd in:Anal Chem
Hoofdauteurs: Li, Dongyang, Cui, Yongliang, Morisseau, Christophe, Gee, Shirley J., Bever, Candace S., Liu, Xiangjiang, Wu, Jian, Hammock, Bruce D., Ying, Yibin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611449/
https://ncbi.nlm.nih.gov/pubmed/28460522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b01247
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