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Multiple signals at the extended 8p23 locus are associated with susceptibility to systemic lupus erythematosus (SLE)
BACKGROUND: A major SLE susceptibility locus lies within a common inversion polymorphism region (encompassing 3.8–4.5 Mb) located at 8p23. Initially implicated genes included FAM167A-BLK and XKR6, of which BLK received major attention due to its known role in B-cell biology. Recently, additional SLE...
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| Publicado no: | J Med Genet |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610905/ https://ncbi.nlm.nih.gov/pubmed/28289186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2016-104247 |
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