Functional polymorphisms of the coagulation factor II gene (F2) and susceptibility to systemic lupus erythematosus (SLE)

OBJECTIVE: Two F2 functional polymorphisms, rs1799963 (G20210A) and rs3136516 (A19911G), are known to be associated with elevated prothrombin (encoded by F2) levels/activity and thrombosis risk. Since systemic lupus erythematosus (SLE) patients have high risk of thrombosis and accelerated atheroscle...

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Main Authors: Demirci, F. Yesim K., Dressen, Amy S., Kammerer, Candace M., Barmada, M. Michael, Kao, Amy H., Ramsey-Goldman, Rosalind, Manzi, Susan, Kamboh, M. Ilyas
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073870/
https://ncbi.nlm.nih.gov/pubmed/21239755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3899/jrheum.100728
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