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Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer's disease mice
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by amyloid-beta (Aβ) plaques and tau neurofibrillary tangles. APPswe/PS1dE9 (APP/PS1) mice have been developed as an AD model and are characterized by plaque formation at 4-6 months of age. Here, we sought to bette...
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| Publicado no: | Hippocampus |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610644/ https://ncbi.nlm.nih.gov/pubmed/28667669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22756 |
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