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No Clinically Relevant Drug-Drug Interactions between Methadone or Buprenorphine-Naloxone and Antiviral Combination Glecaprevir and Pibrentasvir

The combination of glecaprevir (formerly ABT-493), a nonstructural protein 3/4A (NS3/4A) protease inhibitor, and pibrentasvir (formerly ABT-530), an NS5A protein inhibitor, is being developed as treatment for HCV genotype 1 to 6 infection. The pharmacokinetics, pharmacodynamics, safety, and tolerabi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kosloski, Matthew P., Zhao, Weihan, Asatryan, Armen, Kort, Jens, Geoffroy, Pierre, Liu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610490/
https://ncbi.nlm.nih.gov/pubmed/28807904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00958-17
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