miR-19b-3p promotes colon cancer proliferation and oxaliplatin-based chemoresistance by targeting SMAD4: validation by bioinformatics and experimental analyses

BACKGROUND: As a disease with extremely complex molecular mechanisms, many deregulated miRNAs have been identified in colon cancer. Few studies have been performed by using Ingenuity Pathways Analysis (IPA) to predict miRNAs specifically expressed in colon cancer. METHODS: A characteristic microRNA-...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Jiang, Tao, Ye, Ling, Han, Zhongbo, Liu, Yuan, Yang, Yinxue, Peng, Zhihai, Fan, Junwei
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610468/
https://ncbi.nlm.nih.gov/pubmed/28938919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0602-5
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