Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats

Notwithstanding potential neurotoxicity of inhaled titanium dioxide nanoparticles (TiO(2) NPs), the toxicokinetics and consequences on blood-brain barrier (BBB) function remain poorly characterized. To improve risk assessment, we need to evaluate the impact on BBB under realistic environmental condi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Disdier, Clémence, Chalansonnet, Monique, Gagnaire, François, Gaté, Laurent, Cosnier, Frédéric, Devoy, Jérôme, Saba, Wadad, Lund, Amie K., Brun, Emilie, Mabondzo, Aloïse
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610323/
https://ncbi.nlm.nih.gov/pubmed/28939873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12404-5
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