Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat

BACKGROUND: Notwithstanding increasing knowledge of titanium dioxide nanoparticles (TiO(2) NPs) passing through biological barriers, their biodistribution to the central nervous system (CNS) and potential effects on blood-brain barrier (BBB) physiology remain poorly characterized. METHODS: Here, we...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Disdier, Clémence, Devoy, Jérôme, Cosnefroy, Anne, Chalansonnet, Monique, Herlin-Boime, Nathalie, Brun, Emilie, Lund, Amie, Mabondzo, Aloïse
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559366/
https://ncbi.nlm.nih.gov/pubmed/26337446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-015-0102-8
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