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Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane

Signal transduction by receptor tyrosine kinases (RTKs) involves complex ligand- and time-dependent changes in conformation and modification state. High resolution structures are available for individual receptors dimers, but less is known about receptor clusters that form in plasma membranes compos...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Werbin, Jeffrey L., Avendaño, Maier S., Becker, Verena, Jungmann, Ralf, Yin, Peng, Danuser, Gaudenz, Sorger, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610318/
https://ncbi.nlm.nih.gov/pubmed/28939861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12257-y
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