γH2AX, 53BP1 and Rad51 protein foci changes in mesenchymal stem cells during prolonged X-ray irradiation

At high exposure levels ionizing radiation is a carcinogen. Little is known about how human stem cells, which are known to contribute to tumorigenesis, respond to prolonged radiation exposures. We studied formation of DNA double strand breaks, accessed as γH2AX and 53BP1 foci, in human mesenchymal s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tsvetkova, Anastasia, Ozerov, Ivan V., Pustovalova, Margarita, Grekhova, Anna, Eremin, Petr, Vorobyeva, Natalia, Eremin, Ilya, Pulin, Andrey, Zorin, Vadim, Kopnin, Pavel, Leonov, Sergey, Zhavoronkov, Alex, Klokov, Dmitry, Osipov, Andreyan N.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610005/
https://ncbi.nlm.nih.gov/pubmed/28969073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19203
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