Aberrant DNA methylation of GATA binding protein 3 (GATA3), interleukin-4 (IL-4), and transforming growth factor-β (TGF-β) promoters in Behcet's disease

The pathogenesis of Behcet's disease (BD) remains poorly understood. The purpose of this study was to investigate whether an aberrant DNA methylation of transcriptional and inflammatory factors, including TBX21, GATA3, RORγt, FOXP3, IFN-γ, IL-4, IL-17A and TGF-β, in CD4(+)T confers risk to BD....

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Udgivet i:Oncotarget
Main Authors: Zhu, Yunyun, Qiu, Yiguo, Yu, Hongsong, Yi, Shenglan, Su, Wencheng, Kijlstra, Aize, Yang, Peizeng
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610000/
https://ncbi.nlm.nih.gov/pubmed/28969068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19500
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