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Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease

Aberrant methylation change of IRF8 confers risk to various tumors, and abnormal expression of IRF8 is involved in many autoimmune diseases, including ocular Behcet’s disease. However, whether the methylation change of IRF8 is associated with Vogt-Koyanagi-Harada (VKH) disease remains unknown. In th...

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Vydáno v:Sci Rep
Hlavní autoři: Qiu, Yiguo, Yu, Hongsong, Zhu, Yunyun, Ye, Zi, Deng, Jing, Su, Wencheng, Cao, Qingfeng, Yuan, Gangxiang, Kijlstra, Aize, Yang, Peizeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430771/
https://ncbi.nlm.nih.gov/pubmed/28432342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01249-7
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