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Pleiotrophin promotes chemoresistance to doxorubicin in osteosarcoma by upregulating P-glycoprotein

Chemoresistance is a major hindrance to successful treatment of osteosarcoma (OS). Pleiotrophin (PTN), a neurotrophic growth factor, has been linked to the malignant characteristics of various cancer types. We retrospectively examined the correlation between PTN expression and chemoresistance in OS...

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Pubblicato in:Oncotarget
Autori principali: Wu, Dapeng, Liu, Liguo, Yan, Xuebing, Wang, Chunyan, Wang, Yaling, Han, Kun, Lin, Shuchen, Gan, Zhihua, Min, Daliu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609967/
https://ncbi.nlm.nih.gov/pubmed/28969035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19148
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