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Cytosine 5-hydroxymethylation regulates VHL gene expression in renal clear cell carcinoma

Cytosine5-hyxymethylation (5hmC)which is a new epigenetic modification form plays important roles in the development and progression of tumors. In the present study, we observed that levels of 5hmC in the promoter region of Von Hippel-Lindau (VHL) were lower in 97 samples of renal clear cell carcino...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ma, En-Guang, Bai, Yu-Feng, Cao, Wei, Cao, Yan, Huang, Yong-Gang, Cheng, Huan-Chen, An, Rui-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609960/
https://ncbi.nlm.nih.gov/pubmed/28969028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19070
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