Increasing UCP2 expression and decreasing NOX1/4 expression maintain chondrocyte phenotype by reducing reactive oxygen species production

The aim of this study is to demonstrate that improving the mitochondrial function can inhibite the loss of chondrocyte phenotype by regulating the expression of uncoupling protein 2(UCP2) and NADPH oxidase1/4(NOX1/4) to reduce the production of reactive oxygen species(ROS). The effects of mitochondr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Miao, Yansong, Dong, Yuefu, Huang, Ping, Zhao, Xiang, Huang, Zhenyu, Yao, Jufang, Li, He, Xu, Qingrong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609958/
https://ncbi.nlm.nih.gov/pubmed/28969026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18908
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